Stadium: Banterra Center Round: 1
Home Manager: Barry Hinson Away Manager: Jon Harris
| NCAAB | 2016/11/19 01:00 | Southern Illinois v SIU Edwardsville | L | 101-83 |
| NCAAB | 2015/12/10 01:00 | Southern Illinois v SIU Edwardsville | W | 74-76 |
| NCAAB | 2014/12/04 01:00 | SIU Edwardsville v Southern Illinois | L | 67-79 |
| NCAAB | 2011/12/19 12:00 | Southern Illinois v SIU Edwardsville | L | 80-57 |
| NCAAB | 2017/11/25 21:30 | SIU Edwardsville v Creighton | L | 66-103 |
| NCAAB | 2017/11/23 01:00 | Western Illinois v SIU Edwardsville | L | 69-67 |
| NCAAB | 2017/11/18 18:00 | Stetson v SIU Edwardsville | W | 76-80 |
| NCAAB | 2017/11/16 01:00 | Valparaiso v SIU Edwardsville | L | 94-69 |
| NCAAB | 2017/11/11 01:00 | SIU Edwardsville v Purdue | L | 74-105 |
| NCAAB | 2017/02/26 01:00 | Eastern Illinois v SIU Edwardsville | W | 59-78 |
| NCAAB | 2017/02/19 00:30 | Austin Peay v SIU Edwardsville | L | 92-84 |
| NCAAB | 2017/02/17 00:00 | SIU Edwardsville v Murray State | L | 73-84 |
| NCAAB | 2017/11/26 01:00 | Southern Illinois v Murray State | L | 73-81 |
| NCAAB | 2017/11/22 00:00 | Southern Illinois v Louisville | L | 42-84 |
| NCAAB | 2017/11/19 01:00 | Southern Illinois v Illinois Springfield | W | 69-64 |
| NCAAB | 2017/11/11 00:00 | Winthrop v Southern Illinois | W | 66-81 |
| NCAAB | 2017/03/04 20:30 | Southern Illinois v Illinois St | L | 50-63 |
| NCAAB | 2017/03/03 20:00 | Loyola Chicago v Southern Illinois | W | 50-55 |
| NCAAB | 2017/02/26 01:00 | Loyola Chicago v Southern Illinois | W | 70-72 |
| NCAAB | 2017/02/23 00:00 | Illinois St v Southern Illinois | L | 50-46 |