[9] Spartak Moskva 1-1 Lokomotiv Moskva [4] 2021-11-07 16:00
Stadium: Otkritie Arena Round: 14
Referee: Ivan Sidenkov Home Manager: Rui Vitoria Away Manager: Markus Gisdol
Head to Head
| Ryssland - Premier League | 2021/04/11 16:00 | Lokomotiv Moskva v Spartak Moskva | L | 2-0 |
| Ryssland - Premier League | 2020/08/23 16:00 | Spartak Moskva v Lokomotiv Moskva | W | 2-1 |
| Ryssland - Premier League | 2020/07/08 17:30 | Spartak Moskva v Lokomotiv Moskva | D | 1-1 |
| Europa - Vänskapsmatcher | 2020/02/05 15:00 | Spartak Moskva v Lokomotiv Moskva | L | 3-5 |
| Ryssland - Premier League | 2019/10/27 13:30 | Lokomotiv Moskva v Spartak Moskva | W | 0-3 |
| Europa - Vänskapsmatcher | 2019/01/29 17:00 | Spartak Moskva v Lokomotiv Moskva | W | 4-0 |
| Ryssland - Premier League | 2018/12/02 16:00 | Spartak Moskva v Lokomotiv Moskva | W | 2-1 |
| Ryssland - Premier League | 2018/08/04 16:00 | Lokomotiv Moskva v Spartak Moskva | D | 0-0 |
Home History
| UEFA Europa League | 2021/11/04 20:00 | Leicester v Spartak Moskva | D | 1-1 |
| Ryssland - Premier League | 2021/10/30 13:30 | Spartak Moskva v Rostov | D | 1-1 |
| Ryssland - Premier League | 2021/10/24 16:00 | Zenit St Petersburg v Spartak Moskva | L | 7-1 |
| UEFA Europa League | 2021/10/20 14:30 | Spartak Moskva v Leicester | L | 3-4 |
| Ryssland - Premier League | 2021/10/16 16:00 | Spartak Moskva v Dynamo Moskva | D | 2-2 |
| Ryssland - Premier League | 2021/10/03 16:00 | FC Akhmat Grozny v Spartak Moskva | W | 0-1 |
| UEFA Europa League | 2021/09/30 16:45 | Napoli v Spartak Moskva | W | 2-3 |
| Ryssland - Premier League | 2021/09/25 16:00 | Spartak Moskva v FC Ufa | W | 2-0 |
Away History
| UEFA Europa League | 2021/11/04 17:45 | Galatasaray SK v Lokomotiv Moskva | D | 1-1 |
| Ryssland - Premier League | 2021/10/30 16:00 | FC Nizhny Novgorod v Lokomotiv Moskva | W | 1-2 |
| Ryssland - Premier League | 2021/10/25 16:00 | Lokomotiv Moskva v PFC Sochi | W | 2-1 |
| UEFA Europa League | 2021/10/21 19:00 | Lokomotiv Moskva v Galatasaray SK | L | 0-1 |
| Ryssland - Premier League | 2021/10/16 13:30 | Rubin Kazan v Lokomotiv Moskva | D | 2-2 |
| Ryssland - Premier League | 2021/10/03 16:00 | Lokomotiv Moskva v Rostov | L | 1-2 |
| UEFA Europa League | 2021/09/30 19:00 | Lazio v Lokomotiv Moskva | L | 2-0 |
| Ryssland - Premier League | 2021/09/25 11:00 | FK Khimki v Lokomotiv Moskva | D | 0-0 |
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